Endocrine Abstracts

Background: In the 2019 ESC Guidelines on diabetes, pre-diabetes and cardiovascular diseases, only retinopathy appears as a target organ damage as a parameter for stratification patients into very high-risk group. The aim of study was to check the strength of association between DN and isolated DR groups with cardiovascular complications.Methods: Chronic kidney disease (CKD) was defined by eGFR ≤ 59 ml/min/1.73 m2 and proteinuria (P...

Background and aims: The aim of this study was to examine the prevalence of neuropathy and nephropathy in patients with type 2 (T2DM) complicated by proliferate retinopathy (PDR) and coronary artery occlusive disease (CAOD) treated with stent or bypass surgery.Materials and methods: Comparisons were made between 22 patients with T2DM and bypass or stenting of coronary arteries with normal fundoscopic finding (G1) and 21 age matched controls without diabe...

Introduction: The incidence of thyroid nodules is increasing. Fine-needle aspiration (FNA) of all thyroid nodules is unnecessary, but it is necessary to provide a more precise identification of those nodules that are potentially malignant in nature. In the literature there are several suggested systems for assessing malignancy of nodules in the thyroid gland.Objective: To determine the differences between EU and ACR TIRADS recommendation for fine-needle ...

Introduction: 30% of the adult population has high blood pressure. About 6% of the hypertension may be caused by primary aldosteronism and very rare by primary hyperparathyroidism. The combination of these two causes is very rare.Case report: Our patient is women (age 50) with a 21 year long history of uncontrolled hypertension. Treatment of hypertension consist of a beta-blocker, calcium channel blockers, angiotensin converting enzyme inhibitor, loop di...

Introduction: Hypogonadotropic hypogonadism(HH) is mandatory treated with testosterone (T). However, gonadotropin(hCG/FSH) administration might be the challenging optimal therapy.Case 1: Male, 23-y-old, hypophisectomy pp. adenoma hromophobum, one month later- FSH 1.5 U/L, LH 0.55 U/L. Primogonyl(hCG) test; testosteronemia: 0 day 0.069, 3 day 19.01 nmol/l. After 5 m in ejaculate no sperm. 5 m after introduction of hCG twice weekly 1,500 i.u. and FSH+LH 15...

Introduction: Some patients develop excessive bone metabolism supression during antiresorptive therapy. Low remodelling rate enables increase in tissue mineralisation density and homogenicity of bone trabeculae. Increase in density makes micro-damage more likely. Increased homogenicity provides less resistance to spread of the micro-cracks and slowed remodelling slows down removal of microdemage. All this leads to increased bone fragility.Aim: To establi...

The prevalence of osteoporosis among men is not well-documented. The aim of this cross-sectional study is to analyze results of DXA scans preformed in males in Clinical center of Vojvodina between years 2009 and 2016. Form the total of 2006 fist DXA scans performed in 7 years period there was 14.8% of males. DXA scan was indicated by the rheumatologists, internists and endocrinologists predominantly for suspected secondary causes of osteoporosis. We divided male subjects in gr...

Introduction: Phthalates are ubiquitous endocrine disruptors (EDs). EDs induce obesity. MEP and MEHP affect thyroid function.Aim: Estimation of burden of MEP and MEHP in our population, evaluation of leptin in obese MEP and MEHP positive and negative subjects and evaluation of connection between leptin, MEP, MEHP and thyroid indicators in that subgroup. Materials and methods: a cross-sectional study, with 201 subjects divided into MEP/MEHP positive and n...

The data of etiology and clinical characteristics of hypopituitarism in different countries differes. The aim of the study is to investigate etiology and some clinical characteristics of patients with hypopituitarism that were treated in the Clinical center of Vojvodina. The study was conducted as a retrospective study. There were 32 males and 28 female patients. Mean age was 52.2±17.5 years. Data was analized before and after substitution of hypopituitarism. Patients wer...

Introduction: Long-term therapy with bisphosphonates is considered a risk factor for the development of atypical fractures of the femur. One of the mechanisms of these fractures is excessive suppression of bone metabolism. The supplementation dose of vitamin D and calcium could have an impact on the degree of suppression of bone turnover.The aim: To determine whether the presence or dose of supplementation with vitamin D and calcium during antiresorptive...